Annotation Detail

Information
Associated Genes
CFTR
Associated Variants
CFTR p.Arg553Gly (p.R553G) ( ENST00000003084.11, ENST00000648260.1, ENST00000649406.1, ENST00000649781.2, ENST00000699602.1, ENST00000699605.1 )
CFTR p.Arg553Ter (p.R553*) ( ENST00000003084.11, ENST00000648260.1, ENST00000649406.1, ENST00000649781.2, ENST00000699602.1, ENST00000699605.1 )
CFTR p.Arg553Gly (p.R553G) ( ENST00000003084.11, ENST00000648260.1, ENST00000649406.1, ENST00000649781.2, ENST00000699602.1, ENST00000699605.1 )
CFTR p.Arg553Ter (p.R553*) ( ENST00000003084.11, ENST00000648260.1, ENST00000649406.1, ENST00000649781.2, ENST00000699602.1, ENST00000699605.1 )
Associated Disease
cystic fibrosis
Source Database
DisGeNET
Description
We have studied the effects of the stop mutation R553X in exon 11 of the CFTR gene by analyzing mRNA extracted from nasal epithelial cells harvested from patients with cystic fibrosis.
Pubmed
7514569
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.8
Year of publication
1994
Drugs