Annotation Detail
Information
- Associated Genes
- STAT3
- Associated Variants
-
STAT3 c.-2+11876T>C
(
ENST00000389272.7,
ENST00000679185.1,
ENST00000678792.1,
ENST00000678913.1,
ENST00000679014.1,
ENST00000678906.1,
ENST00000677479.1,
ENST00000677723.1,
ENST00000588969.5,
ENST00000678572.1,
ENST00000715205.1,
ENST00000678960.1,
ENST00000678048.1,
ENST00000264657.10,
ENST00000679166.1,
ENST00000678674.1,
ENST00000678535.1,
ENST00000404395.3,
ENST00000677442.1,
ENST00000585517.5,
ENST00000678827.1,
ENST00000678043.1,
ENST00000677152.1,
ENST00000677603.1,
ENST00000678044.1,
ENST00000678905.1,
ENST00000677421.1,
ENST00000677030.1 )
STAT3 c.-2+11876T>C ( ENST00000264657.10, ENST00000389272.7, ENST00000404395.3, ENST00000585517.5, ENST00000588969.5, ENST00000677030.1, ENST00000677152.1, ENST00000677421.1, ENST00000677442.1, ENST00000677479.1, ENST00000677603.1, ENST00000677723.1, ENST00000678043.1, ENST00000678044.1, ENST00000678048.1, ENST00000678535.1, ENST00000678572.1, ENST00000678674.1, ENST00000678792.1, ENST00000678827.1, ENST00000678905.1, ENST00000678906.1, ENST00000678913.1, ENST00000678960.1, ENST00000679014.1, ENST00000679166.1, ENST00000679185.1, ENST00000715205.1 ) - Associated Disease
- colon carcinoma
- Source Database
- DisGeNET
- Description
- We found that rs744166 in STAT3 was associated with colon cancer risk in two studies; however, the direction of the observation was reversed in TP53 mutant tumors possibly due to a nullification of the effect by mutant p53.
- Pubmed
- 25132422
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00678604680200758
- Year of publication
- 2014
Drugs