Annotation Detail
Information
- Associated Genes
- CYP17A1
- Associated Variants
-
CYP17A1 c.-34T>C
(
ENST00000638190.1,
ENST00000638971.1,
ENST00000369887.4,
ENST00000638272.1,
ENST00000639393.1 )
CYP17A1 c.-34T>A ( ENST00000639393.1, ENST00000638272.1, ENST00000369887.4, ENST00000638190.1, ENST00000638971.1 )
CYP17A1 c.-34T>C ( ENST00000369887.4, ENST00000638190.1, ENST00000638272.1, ENST00000638971.1, ENST00000639393.1 )
CYP17A1 c.-34T>A ( ENST00000369887.4, ENST00000638190.1, ENST00000638272.1, ENST00000638971.1, ENST00000639393.1 ) - Associated Disease
- Malignant neoplasm of endometrium
- Source Database
- DisGeNET
- Description
- The position -34T/C variant in CYP17A1 appears to be associated with reduced risk of endometrial cancer, with those homozygous for the variant allele having about half the risk of those homozygous for the wild type.
- Pubmed
- 17110639
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00325730246496364
- Year of publication
- 2007
Drugs