Annotation Detail

Information
Associated Genes
PPIG
Associated Variants
CYP17A1 c.-34T>C ( ENST00000638190.1, ENST00000638971.1, ENST00000369887.4, ENST00000638272.1, ENST00000639393.1 )
CYP17A1 c.-34T>A ( ENST00000639393.1, ENST00000638272.1, ENST00000369887.4, ENST00000638190.1, ENST00000638971.1 )
CYP17A1 c.-34T>C ( ENST00000369887.4, ENST00000638190.1, ENST00000638272.1, ENST00000638971.1, ENST00000639393.1 )
CYP17A1 c.-34T>A ( ENST00000369887.4, ENST00000638190.1, ENST00000638272.1, ENST00000638971.1, ENST00000639393.1 )
Associated Disease
gallbladder carcinoma
Source Database
DisGeNET
Description
However, in the case-only analysis, CYP rs743572 showed association with increased risk of GBC in tobacco users at hetero genotype and dominant models, as compared to non-user GBC patients.
Pubmed
24687554
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2014
Drugs