Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.His187Arg (p.H187R) ( ENST00000379440.9, ENST00000424424.2, ENST00000430350.2, ENST00000457586.2 )
PRNP p.His187Arg (p.H187R) ( ENST00000379440.9, ENST00000424424.2, ENST00000430350.2, ENST00000457586.2 )
Associated Disease
Prion Diseases
Source Database
DisGeNET
Description
A variant of prion encephalopathy associated with the novel H187R mutation in the PRNP gene displays distinctive clinical and immunostaining characteristics that further expand the boundaries of human prion disease.
Pubmed
10953183
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.481088376032419
Year of publication
2000
Drugs