Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Thr183Ala (p.T183A) ( ENST00000379440.9, ENST00000424424.2, ENST00000430350.2, ENST00000457586.2 )
PRNP p.Thr183Ala (p.T183A) ( ENST00000379440.9, ENST00000424424.2, ENST00000430350.2, ENST00000457586.2 )
Associated Disease
Familial Dementia
Source Database
DisGeNET
Description
This mutant is a homolog of the human T183A mutation of PrP(C) that is associated with early onset of familial dementia.
Pubmed
23787697
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2014
Drugs