Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Met232Arg (p.M232R) ( ENST00000424424.2, ENST00000379440.9, ENST00000430350.2, ENST00000457586.2 )
PRNP p.Met232Arg (p.M232R) ( ENST00000430350.2, ENST00000379440.9, ENST00000424424.2, ENST00000457586.2 )
Associated Disease
Creutzfeldt-Jakob disease
Source Database
DisGeNET
Description
To describe the clinical features of Creutzfeldt-Jakob disease with a substitution of arginine for methionine (M232R substitution) at codon 232 (CJD232) of the prion protein gene (PRNP).
Pubmed
17965961
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.858675488785102
Year of publication
2007
Drugs