Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Val180Ile (p.V180I) ( ENST00000379440.9, ENST00000424424.2, ENST00000430350.2, ENST00000457586.2 )
PRNP p.Val180Ile (p.V180I) ( ENST00000457586.2, ENST00000430350.2, ENST00000379440.9, ENST00000424424.2 )
Associated Disease
Creutzfeldt-Jakob disease
Source Database
DisGeNET
Description
The present study reported DWI results in cases of familial CJD with a V180I mutation (CJD180) in the prion protein gene as well as neurological findings.
Pubmed
20051687
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.858675488785102
Year of publication
2009
Drugs