Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Asp178Asn (p.D178N) ( ENST00000430350.2, ENST00000457586.2, ENST00000424424.2, ENST00000379440.9 )
PRNP p.Asp178Asn (p.D178N) ( ENST00000424424.2, ENST00000379440.9, ENST00000457586.2, ENST00000430350.2 )
Associated Disease
fatal familial insomnia
Source Database
DisGeNET
Description
Recombinant human prion protein mutants huPrP D178N/M129 (FFI) and huPrP+9OR (fCJD) reveal proteinase K resistance.
Pubmed
12356908
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.587816554605694
Year of publication
2002
Drugs