Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Asp178Asn (p.D178N) ( ENST00000430350.2, ENST00000457586.2, ENST00000424424.2, ENST00000379440.9 )
PRNP p.Asp178Asn (p.D178N) ( ENST00000424424.2, ENST00000379440.9, ENST00000457586.2, ENST00000430350.2 )
Associated Disease
fatal familial insomnia
Source Database
DisGeNET
Description
Fatal familial insomnia (FFI) is a special subtype of genetic human prion diseases that is caused by the D178N mutation of the prion protein gene (PRNP).
Pubmed
23430483
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.587816554605694
Year of publication
2013
Drugs