Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Asp178Asn (p.D178N) ( ENST00000430350.2, ENST00000457586.2, ENST00000424424.2, ENST00000379440.9 )
PRNP p.Asp178Asn (p.D178N) ( ENST00000424424.2, ENST00000379440.9, ENST00000457586.2, ENST00000430350.2 )
Associated Disease
fatal familial insomnia
Source Database
DisGeNET
Description
These findings underline the clear-cut distinction between the neuropathological features of Creutzfeldt-Jakob disease associated with D178N PRNP mutation and those of fatal familial insomnia.
Pubmed
24118545
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.587816554605694
Year of publication
2013
Drugs