Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Asp178Asn (p.D178N) ( ENST00000430350.2, ENST00000457586.2, ENST00000424424.2, ENST00000379440.9 )
PRNP p.Asp178Asn (p.D178N) ( ENST00000424424.2, ENST00000379440.9, ENST00000457586.2, ENST00000430350.2 )
Associated Disease
Creutzfeldt-Jakob disease
Source Database
DisGeNET
Description
The D178N mutation, known to be linked to 2 different phenotypes: Fatal Familial Insomnia (FFI) and CJD, was not described so far among Jews.
Pubmed
9531435
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.858675488785102
Year of publication
1998
Drugs