Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Asp178Asn (p.D178N) ( ENST00000430350.2, ENST00000457586.2, ENST00000424424.2, ENST00000379440.9 )
PRNP p.Asp178Asn (p.D178N) ( ENST00000424424.2, ENST00000379440.9, ENST00000457586.2, ENST00000430350.2 )
Associated Disease
Creutzfeldt-Jakob disease
Source Database
DisGeNET
Description
Panencephalopathic Creutzfeldt-Jakob disease with distinct pattern of prion protein deposition in a patient with D178N mutation and homozygosity for valine at codon 129 of the prion protein Gene.
Pubmed
24118545
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.858675488785102
Year of publication
2013
Drugs