Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Pro102Leu (p.P102L) ( ENST00000457586.2, ENST00000430350.2, ENST00000379440.9, ENST00000424424.2 )
PRNP p.Pro102Leu (p.P102L) ( ENST00000379440.9, ENST00000457586.2, ENST00000430350.2, ENST00000424424.2 )
Associated Disease
Gerstmann-Straussler-Scheinker Disease
Source Database
DisGeNET
Description
A point mutation of the prion protein gene (PRNP) at codon 102 resulting in the substitution of proline by leucine (P102L) was identified.
Pubmed
20154442
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.600051301892636
Year of publication
2010
Drugs