Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Pro102Leu (p.P102L) ( ENST00000457586.2, ENST00000430350.2, ENST00000379440.9, ENST00000424424.2 )
PRNP p.Pro102Leu (p.P102L) ( ENST00000379440.9, ENST00000457586.2, ENST00000430350.2, ENST00000424424.2 )
Associated Disease
Prion Diseases
Source Database
DisGeNET
Description
Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein.
Pubmed
16597650
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.481088376032419
Year of publication
2006
Drugs