Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Pro102Leu (p.P102L) ( ENST00000457586.2, ENST00000430350.2, ENST00000379440.9, ENST00000424424.2 )
PRNP p.Pro102Leu (p.P102L) ( ENST00000379440.9, ENST00000457586.2, ENST00000430350.2, ENST00000424424.2 )
Associated Disease
Ataxic
Source Database
DisGeNET
Description
Ataxic GSS in families shows genetic linkage to a mutation in the PrP gene leading to the substitution of Leu for Pro at codon 102.
Pubmed
1686599
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Year of publication
1991
Drugs