Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Pro102Leu (p.P102L) ( ENST00000457586.2, ENST00000430350.2, ENST00000379440.9, ENST00000424424.2 )
PRNP p.Pro102Leu (p.P102L) ( ENST00000379440.9, ENST00000457586.2, ENST00000430350.2, ENST00000424424.2 )
Associated Disease
Peripheral neuropathy
Source Database
DisGeNET
Description
Besides occasional PrP plaques and modest spongiform degeneration, Tg(MoPrP-P101L) mice suffered from a myopathy and a peripheral neuropathy.
Pubmed
8698234
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Year of publication
1996
Drugs