Annotation Detail

Information
Associated Genes
PNPLA3
Associated Variants
PNPLA3 p.Ile148Met (p.I148M) ( ENST00000216180.8, ENST00000423180.2 )
PNPLA3 p.Ile148Met (p.I148M) ( ENST00000216180.8, ENST00000423180.2 )
Associated Disease
Liver Cirrhosis, Alcoholic
Source Database
DisGeNET
Description
Systematic review with meta-analysis: the I148M variant of patatin-like phospholipase domain-containing 3 gene (PNPLA3) is significantly associated with alcoholic liver cirrhosis.
Pubmed
25060292
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.126905598933846
Year of publication
2014
Drugs