Annotation Detail

Information
Associated Genes
WFS1
Associated Variants
WFS1 p.Arg611His (p.R611H) ( ENST00000503569.5, ENST00000506362.2, ENST00000226760.5, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1 )
WFS1 p.Arg611His (p.R611H) ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1 )
Associated Disease
psychiatric hospitalization
Source Database
DisGeNET
Description
Wolframin gene polymorphisms, including the H611R polymorphism, are reportedly associated with mood disorders and psychiatric hospitalization, but there is disagreement about the association of this specific variant with suicidality and impulsive traits.
Pubmed
19328217
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2009
Drugs