Annotation Detail
Information
- Associated Genes
- FTO
- Associated Variants
-
VDR p.Ile352= (p.I352=)
(
ENST00000229022.9,
ENST00000550325.5,
ENST00000549336.6,
ENST00000395324.6 )
FTO c.46-13587A>G ( ENST00000637969.1, ENST00000637001.1, ENST00000471389.6, ENST00000636491.1, ENST00000636218.1 )
VDR p.Ile352= (p.I352=) ( ENST00000229022.9, ENST00000395324.6, ENST00000549336.6, ENST00000550325.5 )
FTO c.46-13587A>G ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 ) - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- Analysis of vitamin D receptor (VDR) TaqI (rs731236; T/C) and fat mass and obesity-associated (FTO) (rs9930506; A/T) polymorphisms in 82 obesity subjects and 102 controls showed significant association for VDR TaqI 'T' allele and obesity (OR: 2.07; 1.123-3.816; P=0.019), contributing to an elevated BMI of 3kg/m(2) per risk allele.
- Pubmed
- 23103831
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.4
- Year of publication
- 2013
Drugs