Annotation Detail

Information
Associated Genes
TPH2
Associated Variants
TPH2 p.Pro312= (p.P312=) ( ENST00000333850.4 )
TPH2 p.Pro312= (p.P312=) ( ENST00000333850.4 )
Associated Disease
Mental Depression
Source Database
DisGeNET
Description
[The study suggested that hopelessness, negative life events and family history of suicide were risk factors of attempted suicide in MDD while the TPH2 rs7305115A remained a significant protective predictor of suicide attempts.]
Pubmed
20738857
Original source reporting the Gene Disease association
GAD
DisGENET score for the Gene Disease association
0.0275464508652653
Year of publication
2010
Drugs