Annotation Detail

Information
Associated Genes
CD247
Associated Variants
CD247 c.59-1380T>C ( ENST00000700158.1, ENST00000700109.1, ENST00000362089.10, ENST00000700106.1, ENST00000700105.1, ENST00000700134.1, ENST00000700108.1, ENST00000392122.4, ENST00000700159.1, ENST00000700142.1, ENST00000700165.1, ENST00000700107.1, ENST00000700160.1 )
CD247 c.59-10421A>C ( ENST00000700108.1, ENST00000700134.1, ENST00000700106.1, ENST00000700105.1, ENST00000362089.10, ENST00000700109.1, ENST00000700158.1, ENST00000700107.1, ENST00000700160.1, ENST00000700165.1, ENST00000700142.1, ENST00000392122.4, ENST00000700159.1 )
NUS1 p.Leu210Ser (p.L210S) ( ENST00000368494.4 )
NUS1 p.Leu210Ter (p.L210*) ( ENST00000368494.4 )
CD247 c.59-1380T>C ( ENST00000362089.10, ENST00000392122.4, ENST00000700105.1, ENST00000700106.1, ENST00000700107.1, ENST00000700108.1, ENST00000700109.1, ENST00000700134.1, ENST00000700142.1, ENST00000700158.1, ENST00000700159.1, ENST00000700160.1, ENST00000700165.1 )
CD247 c.59-10421A>C ( ENST00000362089.10, ENST00000392122.4, ENST00000700105.1, ENST00000700106.1, ENST00000700107.1, ENST00000700108.1, ENST00000700109.1, ENST00000700134.1, ENST00000700142.1, ENST00000700158.1, ENST00000700159.1, ENST00000700160.1, ENST00000700165.1 )
NUS1 p.Leu210Ser (p.L210S) ( ENST00000368494.4 )
NUS1 p.Leu210Ter (p.L210*) ( ENST00000368494.4 )
Associated Disease
Autoimmune Diseases
Source Database
DisGeNET
Description
Given the role of CD247 in the response of the T cells, its entailment in autoimmune diseases and in order to better clarify the role of this gene in RA susceptibility, we aimed to analyze CD247 gene variants previously associated with other autoimmune diseases (rs1052237, rs2056626 and rs864537) in a large independent European Caucasian population.
Pubmed
23861880
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00399568321108385
Year of publication
2013
Drugs