Annotation Detail

Information
Associated Genes
GJB2
Associated Variants
GJB2 p.Gly45Glu (p.G45E) ( ENST00000382844.2, ENST00000382848.5 )
GJB2 p.Gly45Glu (p.G45E) ( ENST00000382844.2, ENST00000382848.5 )
Associated Disease
Sensorineural Hearing Loss (disorder)
Source Database
DisGeNET
Description
The G45E mutation was not reported previously in Caucasian patients but was the third most common GJB2 mutation (16% of disease alleles) in Japanese patients with autosomal recessive non-syndromic HL.
Pubmed
15633193
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.344722343815082
Year of publication
2005
Drugs