Annotation Detail
Information
- Associated Genes
- RUNX1T1
- Associated Variants
-
RUNX1T1 MUTATION
RUNX1T1 MUTATION - Associated Disease
- core binding factor acute myeloid leukemia
- Source Database
- DisGeNET
- Description
- Core Binding Factor acute myeloid leukemia (CBF-AML) with t(8;21) RUNX1-MTG8 or inv(16) CBFB-MYH11 fusion proteins often show upregulation of wild type or mutated KIT receptor.
- Pubmed
- 25612891
- Section of the abstract supporting the evidence
- BACKGROUND
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs