Annotation Detail

Information
Associated Genes
FTO
Associated Variants
FTO c.46-10447T>C ( ENST00000637969.1, ENST00000637001.1, ENST00000471389.6, ENST00000636491.1, ENST00000636218.1 )
FTO c.46-10447T>C ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
Associated Disease
Metabolic syndrome X
Source Database
DisGeNET
Description
The C allele of the rs7204609 polymorphism in the FTO gene increased the chance for the presence of MetS, especially central obesity, and microalbuminuria, independently of energy and nutrient intakes in this sample of type 2 diabetic patients from Southern Brazil.
Pubmed
21741858
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.140097968187258
Year of publication
2012
Drugs