Annotation Detail

Information
Associated Genes
BDNF
Associated Variants
BDNF MUTATION
BDNF MUTATION
Associated Disease
Triple Negative Breast Neoplasms
Source Database
DisGeNET
Description
Using patient-derived specimens, we demonstrated the existence of paracrine brain-derived neurotrophic factor (BDNF) signaling between differentiated recurrent TNBC cells and CSCs characterized by the expression of TrkB, the receptor of BDNF.
Pubmed
24531713
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs