Annotation Detail

Information
Associated Genes
PGR
Associated Variants
PGR MUTATION
PGR MUTATION
Associated Disease
Triple Negative Breast Neoplasms
Source Database
DisGeNET
Description
Particularly breast cancers, which do not express estrogen receptor α (ERα) and progesterone receptor (PR) and which have no overexpression of human epidermal growth factor receptor 2 (HER2), so-called triple-negative breast cancers (TNBCs), are considered as very aggressive and have a poor prognosis.
Pubmed
25420519
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0162865123248182
Drugs