Annotation Detail

Information
Associated Genes
PON1
Associated Variants
PON1 c.-108C>T
PON1 c.-108C>T
Associated Disease
childhood brain tumor
Source Database
DisGeNET
Description
[Brain tumors in children, especially primitive neuroectodermal tumors, are associated with the PON1 C-108T allele associated with reduced ability to detoxify insecticides common in children\'s homes at the time of the study. Significant gene-environment i]
Pubmed
16002382
Original source reporting the Gene Disease association
GAD
DisGENET score for the Gene Disease association
0.00473406395720406
Year of publication
2005
Drugs