Annotation Detail
Information
- Associated Genes
- SF3B2
- Associated Variants
-
SF3B2 MUTATION
SF3B2 MUTATION - Associated Disease
- Progressive cGVHD
- Source Database
- DisGeNET
- Description
- Acquired defects in the p53 pathway, activating mutations of NOTCH1, and dysfunctional mutations of SF3B1 and BIRC3 identify patients with higher risk of progressive disease, poorer responses to conventional chemoimmunotherapy, and shorter survival.
- Pubmed
- 25696844
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs