Annotation Detail
Information
- Associated Genes
- PRKDC
- Associated Variants
-
PRKDC c.6464+375G>T
(
ENST00000314191.7,
ENST00000338368.7 )
PRKDC c.6465+375G>T ( ENST00000314191.7, ENST00000338368.7 ) - Associated Disease
- glioblastoma
- Source Database
- DisGeNET
- Description
- A 44% increase in risk for glioblastoma multiforme was found for individuals homozygous for the G allele of the PRKDC rs7003908 variant (odds ratio(GG), 1.44; 95% confidence interval, 1.13-1.84); there was a statistically significant trend (P = 0.009) with increasing number of G alleles.
- Pubmed
- 19318434
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00381011773078838
- Year of publication
- 2009
Drugs