Annotation Detail
Information
- Associated Genes
- TCF7L2
- Associated Variants
-
rs6983267
(
ENST00000645438.1 )
rs6983267 ( ENST00000645438.1 ) - Associated Disease
- colorectal cancer
- Source Database
- DisGeNET
- Description
- In our previous work, we showed that the colorectal cancer (CRC) risk variant rs6983267 at 8q24 resides within a TCF4 binding site at the MYC-335 enhancer, with the risk allele G having a stronger binding capacity and Wnt responsiveness.
- Pubmed
- 22429595
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.135863180712497
- Year of publication
- 2012
Drugs