Annotation Detail

Information
Associated Genes
TCF7L2
Associated Variants
rs6983267 ( ENST00000645438.1 )
rs6983267 ( ENST00000645438.1 )
Associated Disease
colon carcinoma
Source Database
DisGeNET
Description
We show that the beta-catenin-TCF4 transcription factor complex binds preferentially to the cancer risk-associated rs6983267(G) allele in colon cancer cells.
Pubmed
20065031
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00434306995328485
Year of publication
2010
Drugs