Annotation Detail
Information
- Associated Genes
- MIR449A
- Associated Variants
-
NFKBIA c.*126G>A
(
ENST00000557140.5,
ENST00000697961.1,
ENST00000557389.1,
ENST00000216797.10 )
NFKBIA c.*126G>A ( ENST00000216797.10, ENST00000557140.5, ENST00000557389.1, ENST00000697961.1 ) - Associated Disease
- Nasopharyngeal carcinoma
- Source Database
- DisGeNET
- Description
- The rs696AA variant in IκBα had an increased risk of NPC (OR = 1.41, 95% CI = 1.20-1.66, and P = 2.28 × 10(-5)) by decreasing IκBα expression due to the modulation of microRNA hsa-miR-449a.
- Pubmed
- 26161396
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2014
Drugs