Annotation Detail

Information
Associated Genes
MTHFD1L
Associated Variants
MTHFD1L c.1260-4955G>A ( ENST00000367321.8, ENST00000611279.4, ENST00000618312.4 )
MTHFD1L c.1260-4955G>A ( ENST00000367321.8, ENST00000611279.4, ENST00000618312.4 )
Associated Disease
Acute coronary syndrome
Source Database
DisGeNET
Description
After Cox adjustment for other ACS risk factors, of 95 SNPs tested in 811 whites only the association with the rs6922269 in MTHFD1L was statistically significant, with a 2.6-fold mortality hazard (P = 0.007).
Pubmed
21957892
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2011
Drugs