Annotation Detail

Information
Associated Genes
APOE
Associated Variants
LDLR p.Asn591= (p.N591=) ( ENST00000252444.10, ENST00000455727.6, ENST00000535915.5, ENST00000545707.5, ENST00000557933.5, ENST00000558013.5, ENST00000558518.6, ENST00000560467.2 )
LDLR p.Asn591= (p.N591=) ( ENST00000252444.10, ENST00000455727.6, ENST00000535915.5, ENST00000545707.5, ENST00000557933.5, ENST00000558013.5, ENST00000558518.6, ENST00000560467.2 )
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
Our results not only demonstrated potential interactions of APOE epsilon2/epsilon3/epsilon4 and LDLR C1773T polymorphisms with risk of having ischemic stroke, but also added the evidence of independent role of hypertension and APOE epsilon2/epsilon3/epsilon4 polymorphism in the development of this disorder in Northern Han Chinese.
Pubmed
18851860
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.291129116755292
Year of publication
2009
Drugs