Annotation Detail
Information
- Associated Genes
- PPARG
- Associated Variants
-
PPARG MUTATION
PPARG MUTATION - Associated Disease
- Pulmonary arterial hypertension
- Source Database
- DisGeNET
- Description
- We showed that miR-27b plays a role endothelial function and NO release and elucidated a potential mechanism by which miR-27b regulates Hsp90-eNOS and NO signaling by modulating PPARγ expression, providing potential therapeutic targets for the treatment of PAH.
- Pubmed
- 25795136
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00135720936040152
Drugs