Annotation Detail

Information
Associated Genes
RAF1
Associated Variants
RAF1 MUTATION
RAF1 MUTATION
Associated Disease
Pulmonary arterial hypertension
Source Database
DisGeNET
Description
The RAF1 gene encodes Raf-1 kinase, part of the Ras/mitogen-activated kinase (MAPK) signaling pathway, which has been linked to the development of PAH.
Pubmed
25706034
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs