Annotation Detail
Information
- Associated Genes
- NR1I2
- Associated Variants
-
ENSG00000285585 c.*2-24111G>A, NR1I2 c.95+266G>A
(
ENST00000337940.4,
ENST00000466380.6,
ENST00000393716.8 )
NR1I2 c.912-93G>A ( ENST00000337940.4, ENST00000393716.8, ENST00000466380.6 )
ENSG00000285585 c.*2-24111G>A, NR1I2 c.95+266G>A ( ENST00000337940.4, ENST00000393716.8, ENST00000466380.6 )
NR1I2 c.912-93G>A ( ENST00000337940.4, ENST00000393716.8, ENST00000466380.6 ) - Associated Disease
- ulcerative colitis
- Source Database
- DisGeNET
- Description
- PXR A7635G (rs6785049) variant genotype was associated with a higher risk of UC diagnosis before the age of 40 years and with a higher risk of extensive disease (OR: 1.34, 95% CI: 1.03-1.75 and OR: 2.49, 95% CI: 1.24-5.03, respectively).
- Pubmed
- 21245992
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0102587093122591
- Year of publication
- 2011
Drugs