Annotation Detail

Information
Associated Genes
COASY
Associated Variants
COASY MUTATION
COASY MUTATION
Associated Disease
Neurodegeneration with brain iron accumulation (NBIA)
Source Database
DisGeNET
Description
Mutations in PANK2 and CoASY, both implicated in CoA biosynthesis that acts as a fatty acyl carrier, lead, respectively, to PKAN and CoPAN forms of NBIA.
Pubmed
25668476
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs