Annotation Detail

Information
Associated Genes
ALDH2
Associated Variants
ALDH2 p.Glu504Lys (p.E504K) ( ENST00000261733.7, ENST00000416293.7 )
ALDH2 p.Glu504Lys (p.E504K) ( ENST00000261733.7, ENST00000416293.7 )
Associated Disease
myocardial infarction
Source Database
DisGeNET
Description
Emerging evidence has shown that the common rs671 G>A (Glu504Lys) polymorphism in the ALDH2 gene might play a critical role in increasing the susceptibility to coronary heart disease (CHD), including myocardial infarction (MI); however, individually published studies showed inconclusive results.
Pubmed
23697560
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.012268423026996
Year of publication
2013
Drugs