Annotation Detail

Information
Associated Genes
LGR6
Associated Variants
LGR6 c.213-7375G>A ( ENST00000367278.8, ENST00000255432.11, ENST00000439764.2 )
LGR6 c.213-7375G>A ( ENST00000255432.11, ENST00000367278.8, ENST00000439764.2 )
Associated Disease
Malignant neoplasm of breast
Source Database
DisGeNET
Description
SNPs at four loci, 1q32.1 (MDM4, P = 2.1 × 10(-12) and LGR6, P = 1.4 × 10(-8)), 2p24.1 (P = 4.6 × 10(-8)) and 16q12.2 (FTO, P = 4.0 × 10(-8)), were associated with ER-negative but not ER-positive breast cancer (P > 0.05).
Pubmed
23535733
Original source reporting the Gene Disease association
GWASCAT
DisGENET score for the Gene Disease association
0.120542883744161
Year of publication
2013
Drugs