Annotation Detail

Information
Associated Genes
FLT3
Associated Variants
FLT3 MUTATION
FLT3 MUTATION
Associated Disease
acute myeloid leukemia with mutated CEBPA
Source Database
DisGeNET
Description
Our data confirm that dmCEBPA but not smCEBPA is prognostically favorable in NPM1(wt)FLT3-ITD(wt) AML, and suggest that the entity AML with mutated CEBPA should be definitely designated as AML with dmCEBPA in WHO classification and smCEBPA should be excluded from the favorable risk of molecular abnormalities.
Pubmed
25400766
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs