Annotation Detail

Information
Associated Genes
HLA-DRB1
Associated Variants
HLA-DRB1 MUTATION
HLA-DRB1 MUTATION
Associated Disease
Kashin-Beck Disease
Source Database
DisGeNET
Description
HLA-DRB1 and CD2AP gene were identified to be among the susceptibility genes of KBD, thus supporting the role of the autoimmune response in KBD and the possibility of shared etiology between osteoarthritis, rheumatoid arthritis, and KBD.
Pubmed
24776925
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs