Annotation Detail
Information
- Associated Genes
- NRXN3
- Associated Variants
-
NRXN3 c.3444+11417A>G
(
ENST00000679122.1,
ENST00000676811.1,
ENST00000281127.11,
ENST00000555387.1,
ENST00000428277.6,
ENST00000554738.5,
ENST00000335750.7,
ENST00000554719.5,
ENST00000634499.2,
ENST00000557594.5 )
rs2605100
TFAP2B c.602-724A>G ( ENST00000393655.4 )
rs545854
NRXN3 c.3444+11417A>G ( ENST00000281127.11, ENST00000335750.7, ENST00000428277.6, ENST00000554719.5, ENST00000554738.5, ENST00000555387.1, ENST00000557594.5, ENST00000634499.2, ENST00000676811.1, ENST00000679122.1 )
rs2605100
TFAP2B c.602-724A>G ( ENST00000393655.4 )
rs545854 - Associated Disease
- Obesity, Abdominal
- Source Database
- DisGeNET
- Description
- Two meta-analyses of genome-wide association studies (GWAS) have suggested that four variants: rs2605100 in lysophospholipase-like 1 (LYPLAL1), rs10146997 in neuroxin 3 (NRXN3), rs545854 in methionine sulfoxide reductase A (MSRA), and rs987237 in transcription factor activating enhancer-binding protein 2 beta (TFAP2B) associate with measures of central obesity.
- Pubmed
- 21674055
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2011
Drugs