Annotation Detail

Information
Associated Genes
GLE1
Associated Variants
GLE1 MUTATION
GLE1 MUTATION
Associated Disease
Lethal Arthrogryposis With Anterior Horn Cell Disease
Source Database
DisGeNET
Description
Lethal congenital contracture syndrome 1 and lethal arthrogryposis with anterior horn cell disease are autosomal recessive fetal motor neuron diseases that are caused by mutations in another global RNA-processing protein, hGle1.
Pubmed
25343993
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,CLINVAR,CTD_human,ORPHANET,UNIPROT
DisGENET score for the Gene Disease association
0.480542883744161
Drugs