Annotation Detail
Information
- Associated Genes
- STAT5A
- Associated Variants
-
STAT5A MUTATION
STAT5A MUTATION - Associated Disease
- T-cell prolymphocytic leukemia
- Source Database
- DisGeNET
- Description
- Importantly, primary T-PLL cells exhibited constitutive activation of STAT5, and targeted pharmacologic inhibition of STAT5 with pimozide induced apoptosis in primary T-PLL cells.
- Pubmed
- 24825865
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs