Annotation Detail

Information
Associated Genes
NR1I2
Associated Variants
NR1I2 MUTATION
NR1I2 MUTATION
Associated Disease
liver carcinoma
Source Database
DisGeNET
Description
For CYP3 family, the expression of PXR was decreased 60% in HCC, together with decreases in CYP3A4, CYP3A5, and CYP3A7.
Pubmed
25024626
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00407162808120455
Drugs