Annotation Detail
Information
- Associated Genes
- NR1I2
- Associated Variants
-
NR1I2 MUTATION
NR1I2 MUTATION - Associated Disease
- liver carcinoma
- Source Database
- DisGeNET
- Description
- This novel PXR isoform, displaying a dominant-negative activity and regulated by DNA methylation, is associated with outcomes of patients with HCC treated by resection, suggesting that it represents a key modulator of PXR.
- Pubmed
- 24798619
- Section of the abstract supporting the evidence
- CONCLUSIONS
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00407162808120455
Drugs