Annotation Detail

Information
Associated Genes
CYP21A2
Associated Variants
CYP21A2 p.Pro31Leu (p.P31L) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Ile173Asn (p.I173N) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Pro31Leu (p.P31L) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Ile173Asn (p.I173N) ( ENST00000435122.3, ENST00000644719.2 )
Associated Disease
congenital adrenal hyperplasia
Source Database
DisGeNET
Description
We hereby describe our recent experience with the pregnancy of a patient who had congenital adrenal hyperplasia due to a rare combination of P30L/I172N mutations in the CYP21 (21-hydroxylase) gene.
Pubmed
14664429
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.29375669260601
Year of publication
2003
Drugs