Annotation Detail

Information
Associated Genes
CYP21A2
Associated Variants
CYP21A2 p.Ile173Asn (p.I173N) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Ile173Asn (p.I173N) ( ENST00000435122.3, ENST00000644719.2 )
Associated Disease
Chronic active hepatitis
Source Database
DisGeNET
Description
To assess the contributions of pre- and postnatal androgens, the CAH subjects were categorized into genotype groups (G) according to the reported severity of loss of CYP21 function: G1 (n = 10, null mutations), G2 (n = 9, intron 2G), G3 (n = 3, I172N), and G4 (n = 2, unknown loss of function).
Pubmed
14715880
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0423449320445273
Year of publication
2004
Drugs